Florida Dental Supply
  • HOME
  • EQUIPMENT expand
    • Chairs
      • Orthodontic Line
      • Operatory Line
      • Surgery Line
    • Stools
      • Doctor
      • Assistant
    • Delivery Units
    • Cuspidors
    • Operatory Ligths
      • LED
      • Halogen
    • Mobile Cabinets
    • Vacuum Pumps
      • Dry
      • Wet Ring
    • Air Compressors
      • Lubricated
      • Oil-Less Air Compressors
    • Sterilizers Autoclaves
      • Automatic
      • Manual
      • Accesories
    • Ultrasonic Cleaners
    • Curing Light
    • Endo Handpieces
    • Laboratory
      • Electric Micromotor
      • Vacuum-Forming Machines
      • Vibrators
      • Model Trimmers
    • Scaler Units
      • Ultrasonic Units
      • Piezo Electric Unit
    • Scaler Inserts
      • Ultrasonic Inserts
      • Piezo Electronic Inserts
    • Intraoral Cameras
    • Implant Surgical Units
    • X-Rays Panoramic
      • 2D
      • 3D
    • X-Ray Intraoral
    • X-Ray Intraoral Digital Sensor
  • Main Categories expand
    • ACRYLICS
    • ALLOYS
    • ANESTHETICS
    • ARTICULATING PRODUCTS
    • BUR CARBIDES
    • BURS DIAMONDS
    • BUR ACCESSORIES
    • CEMENTS & LINERS
    • CORE MATERIAL
    • COSMETIC DENTISTRY
    • CROWN & BRIDGE
    • DISPOSABLES
    • ENDODONTICS
    • IMPLANTS
    • EVACUATION PRODUCTS
    • FINISHING & POLISHING
    • HANDPIECES
    • IMPRESSION PRODUCTS
    • INFECTION CONTROL
    • INSTRUMENTS
    • LABORATORY PRODUCTS
    • MATRIX MATERIALS
    • PINS & POSTS
    • PREVENTIVES
    • RETRACTION MATERIALS
    • WAXES
    • RUBBER DAM
    • SURGICAL PRODUCTS
    • X-RAY PRODUCTS
  • NEWS
  • Catalog
  • Contact Us
  • About Us
Florida Dental Supply
clear
  • HOME
  • EQUIPMENT
    • Chairs
      • Orthodontic Line
      • Operatory Line
      • Surgery Line
    • Stools
      • Doctor
      • Assistant
    • Delivery Units
    • Cuspidors
    • Operatory Ligths
      • LED
      • Halogen
    • Mobile Cabinets
    • Vacuum Pumps
      • Dry
      • Wet Ring
    • Air Compressors
      • Lubricated
      • Oil-Less Air Compressors
    • Sterilizers Autoclaves
      • Automatic
      • Manual
      • Accesories
    • Ultrasonic Cleaners
    • Curing Light
    • Endo Handpieces
    • Laboratory
      • Electric Micromotor
      • Vacuum-Forming Machines
      • Vibrators
      • Model Trimmers
    • Scaler Units
      • Ultrasonic Units
      • Piezo Electric Unit
    • Scaler Inserts
      • Ultrasonic Inserts
      • Piezo Electronic Inserts
    • Intraoral Cameras
    • Implant Surgical Units
    • X-Rays Panoramic
      • 2D
      • 3D
    • X-Ray Intraoral
    • X-Ray Intraoral Digital Sensor
  • Main Categories
    • ACRYLICS
    • ALLOYS
    • ANESTHETICS
    • ARTICULATING PRODUCTS
    • BUR CARBIDES
    • BURS DIAMONDS
    • BUR ACCESSORIES
    • CEMENTS & LINERS
    • CORE MATERIAL
    • COSMETIC DENTISTRY
    • CROWN & BRIDGE
    • DISPOSABLES
    • ENDODONTICS
    • IMPLANTS
    • EVACUATION PRODUCTS
    • FINISHING & POLISHING
    • HANDPIECES
    • IMPRESSION PRODUCTS
    • INFECTION CONTROL
    • INSTRUMENTS
    • LABORATORY PRODUCTS
    • MATRIX MATERIALS
    • PINS & POSTS
    • PREVENTIVES
    • RETRACTION MATERIALS
    • WAXES
    • RUBBER DAM
    • SURGICAL PRODUCTS
    • X-RAY PRODUCTS
  • NEWS
  • Catalog
  • Contact Us
  • About Us
 
  • Login
    Login
    Create account
    Forgot your password?
  • Create account
  • track your order
Florida Dental Supply



  • Login
  • My Wishlist
  • Order History
  • Checkout
  • Buy on credit


Your cart is currently empty.

Continue Shopping

Your Products Price
Subtotal: $0.00
View cart Checkout
 
  • My Wishlist
  • 0 item - My Cart - $0.00

    Your cart is currently empty.

    Continue Shopping

    Your Products Price
    Subtotal: $0.00
    View cart Checkout
  1. Home
  2. News
  3. New hope for patients with severe bone loss

New hope for patients with severe bone loss

November 22, 2022

An innovative technology developed at Tel Aviv University will enable bone regeneration to correct large bone defects by means of a special hydrogel. Following successful tests in an animal model, the researchers now plan to move forward to clinical trials.

The groundbreaking study was conducted by experts from TAU's Maurice and Gabriela Goldschleger School of Dental Medicine, led by Prof. Lihi Adler-Abramovich and Dr. Michal Halperin-Sternfeld, in collaboration with Prof. Itzhak Binderman, Dr. Rachel Sarig, Dr. Moran Aviv, and researchers from the University of Michigan in Ann Arbor. The paper was published in the Journal of Clinical Periodontology.

Prof. Adler-Abramovich: "Small bone defects, such as fractures, heal spontaneously, with the body restoring the lost bone tissue. The problem begins with large bone defects. In many cases, when substantial bone loss results from tumor resection (removal by surgery) , physical trauma, tooth extraction, gum disease or inflammation around dental implants, the bone is unable to renew itself. In the current study, we developed a hydrogel that mimics the natural substances in the extracellular matrix of bones, stimulating bone growth and reactivating the immune system to accelerate the healing process."

The researchers explain that the extracellular matrix is the substance surrounding our cells, providing them with structural support. Every type of tissue in our body has a specific extracellular matrix consisting of suitable substances with the right mechanical properties. The new hydrogel has a fibrillary structure that mimics that of the extracellular matrix of the natural bone. Furthermore, it is rigid, thus enabling the patient's cells to differentiate into bone-forming cells.

"As can be expected, the extracellular matrix of our bones is quite rigid," says Prof. Adler-Abramovich. "In our study, we produced a hydrogel that mimics this specific matrix in both chemical and physical properties. At the nanometric level, the cell can attach itself to the gel, gaining structural support and receiving relevant mechanical signals from the fibers. At first, to test these properties, we grew cells in a 3D model of the gel. Then we examined the impact of the hydrogel on model animals with large bone defects that could not heal spontaneously. We monitored them for two months with various methods, including Micro C.T. To our delight, the bone defects were fully corrected through regeneration, with the bones regaining their original thickness, and generating new blood vessels."

According to Prof. Adler-Abramovich, the innovative gel has extensive clinical applications in both orthopedic and dental medicine: "When we lose teeth due to extensive damage or bacterial infections, the standard treatment is dental implants. Implants, however, must be anchored in a sufficient amount of bone, and when bone loss is too substantial, physicians implant additional bone from a healthy part of the body -- a complex medical procedure. Another option is adding bone substitutes from either human or animal sources, but these might generate an immune response. I hope that in the future the hydrogel we have developed will enable faster, safer, and simpler bone restoration."


Story Source:

Materials provided by Tel-Aviv University. Note: Content may be edited for style and length.

FROM: https://www.sciencedaily.com/releases/2022/11/221109124400.htm

Share Share on Facebook Pin it Pin on Pinterest Tweet Tweet on Twitter

Signup For Newsletter

We’ll never share your email address with a third-party.

SOCIAL MEDIA

    Florida Dental Supply
  • Miami Florida
  • (786)-558-9455
  • info@floridadentalsupply.com
  • Open time: 9:00AM - 5:00PM

SOCIAL MEDIA

  • Facebook
  • Instagram

Company Pledge

Florida Dental Supply has been in the market for almost two decades and since the first day the company’s goal has been to provide our dental professionals with the best customer service, quality dental products and recognized and respected brand equipment.

© 2019 Florida Dental Supply. Designed by Florida Dental Supply All Rights Reserved
Collection tune My Account supervisor_account Recent View Product wb_sunny
All Collection ×
  • ACRYLICS
  • ALLOYS
  • ANESTHETICS
  • ARTICULATING PRODUCTS
  • Assistant
  • BLEACHING AND TOOTH WHITENING
  • BONDING SYSTEMS
  • BUR ACCESSORIES
  • BUR CARBIDES
  • BURS DIAMONDS
  • CEMENTS & LINERS
  • Chairs
  • CORE MATERIAL
  • COSMETIC DENTISTRY
  • CROWN & BRIDGE
  • Curing Light
  • Cuspidors
  • Daily Deals 01
  • Delivery Units
  • DISPOSABLES
  • Doctor
  • Dry Vacuum Pump
  • Electric Micromotors
  • Endo Handpieces
  • ENDODONTICS
  • EQUIPMENT
  • EVACUATION PRODUCTS
  • FINISHING & POLISHING
  • Halogen
  • HANDPIECES
  • Home page
  • IMPLANTS
  • IMPRESSION PRODUCTS
  • INFECTION CONTROL
  • INSTRUMENTS
  • Intra-Oral Cameras
  • Intra-Oral Digital Sensor
  • LABORATORY PRODUCTS
  • LED
  • Lubricated Air Compressors
  • MATRIX MATERIALS
  • Mobile Cabinets
  • Oil-less Air Compressors
  • Operatory Line
  • Orthodontic Line
  • Panoramic 2D
  • Panoramic 3D
  • Piezo Electric Inserts
  • Piezo Electric Unit
  • PINS & POSTS
  • PREVENTIVES
  • RETRACTION MATERIALS
  • RUBBER DAM
  • SELF ETCH BONDING SYSTEMS
  • Sterilizers Accessories
  • Sterilizers Automatic
  • Sterilizers Manual
  • SURGERY LINE
  • SURGICAL PRODUCTS
  • Surgical Unit
  • Trimmers
  • Ultrasonic Cleaners
  • Ultrasonic Inserts
  • Ultrasonic Scalers
  • UNIVERSAL COMPOSITES
  • Vacuum Forming
  • Vibrators
  • WAXES
  • Wet Ring
  • X-Ray Intraoral
  • X-Ray Mobile
  • X-Ray Portable
  • X-RAY PRODUCTS
  • X-Ray Wall
My Account ×
history
History
add_shopping_cart
Shopping Cart
lock_open
Login
how_to_reg
Register
supervisor_account
My Account
event_note
Order History
Recent Viewed Products ×

Added To Your Shopping Cart!

 

 

+
-